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US 12,553,902 B2Granted
Methods, kits and compositions for diagnosing and treating renal disease
AssigneeHill's Pet Nutrition, Inc.
InventorsDayakar Badri, Dennis Jewell
Life of this patent
Estimating the term…
Abstract
Methods and kits for assessing the propensity of developing urolithiasis, kidney disease, or bladder disease in pets; and compositions to treat such conditions are described herein.
Claims7
A method of identifying and treating a companion animal at an increased likelihood of developing urolithiasis, comprising:
- analyzing a biological sample obtained from the companion animal for the presence of a tryptophan/kynurenine pathway metabolite;
- an aminosugar pathway metabolite, a phosphatidylcholine pathway metabolite;
- a sphingolipid pathway metabolite and/or a purine pathway metabolite;
- wherein an elevated level of the tryptophan/kynurenine pathway metabolite;
- the aminosugar pathway metabolite, the phosphatidylcholine pathway metabolite;
- the sphingolipid pathway metabolite and/or the purine pathway metabolite indicates that the companion animal has an increased likelihood of developing urolithiasis;
- and
- administering to the companion animal a composition comprising an effective amount of (1) arginine;
- (2) polyunsaturated fatty acids, controlled minerals, and protein;
- or (3) palatability enhancers and viscous water.
7 more elements
Dependencies are inferred from the claim text.