Methods and kits for quantifying the removal of mock virus particles from a purified solution
AssigneeCygnus Technologies, L.L.C.
InventorsDavid Cetlin, Arun Dhar
Life of this patent
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Abstract
The present invention relates to a method of quantifying the amount of Mock Virus Particles (MVP) removed from a solution as a result of processing that solution through a purification technique. This method involves the steps of adding MVP to a solution, processing the solution through a purification technique, quantifying the amount of MVP removed from the solution. The present invention also relates to a kit that can be used in conjunction with the method. This kit will comprise at least one stock solution of MVP and at least one quantification solution.
Claims4
A kit comprising a Mouse Minute Virus (MMV) Mock Viral Particle (MVP) stock solution comprising a modified MMV MVP, wherein the MMV MVP is a non-infectious, non-replicating assembled unit comprising a MMV VP2 viral capsid protein comprising an amino acid sequence having at least 99% identity to SEQ ID NO:
- 6, wherein the stock solution comprises at least 1×107 MMV MVP/ml of the MMV MVP, and wherein non-MMV MVP proteins are less than 5% of all proteins in the stock solution.
Dependencies are inferred from the claim text.