Devices, systems, and methods for continuous real time blood culture measurement
AssigneeBecton, Dickinson and Company
InventorsJames R. Petisce, Adam Steel, Robert E. Armstrong, David J. Turner, Richard Ivey
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Abstract
Provided herein are devices, systems, and methods for measuring the presence of an analyte of interest in a sample. Certain embodiments of the present disclosure are related to culture measurement systems that include a culture vial and a sensor, wherein the sensor is a pH sensor, a responsive label, or an indicator compound, such that the sensor is incorporated into the culture vial for measurement of the pH of the sample.
Claims13
A culture vial for measuring blood culture pH, the culture vial comprising a pH sensor positioned on an interior surface of the blood culture vial, and configured to transmit a signal of pH measurement,
- wherein the culture vial is a blood culture bottle including a liquid media which supports the growth of pathogens within the bottle, wherein the bottle comprises a neck portion comprising an opening at the top of the neck portion, and a septum that caps the opening in the neck of the blood culture bottle, wherein the volume of the blood culture bottle is sufficient to receive a blood sample of 10 ml,
- wherein the pH sensor is an ion specific field effect transistor, or an ion selective electrode, and
- i.) wherein the pH sensor comprises electrical leads that pass through the blood culture vial and are configured to connect to a reader configured to obtain the signal from the pH sensor;
- or
- ii.) wherein the pH sensor is configured to wirelessly communicate with a reader configured to obtain the signal from the pH sensor.
Dependencies are inferred from the claim text.