Polylysine polymers with antimicrobial and/or anticancer activity
AssigneesInternational Business Machines Corporation, Agency for Science, Technology and Research
InventorsNathaniel H. Park, James L. Hedrick, Victoria A. Piunova, Gavin Jones, Yi Yan Yang, Pang Kern Jeremy Tan, Chuan Yang, Cherylette Anne Alexander
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Abstract
Techniques regarding guanidinium functionalized polylysine polymers that can have antimicrobial and/or anticancer activity are provided. For example, one or more embodiments described herein can comprise a chemical composition, which can comprise a polymer comprising a molecular backbone covalently bonded to a pendent guanidinium functional group, wherein the molecular backbone can comprise a polylysine structure.
Claims20
A method, comprising:
- inhibiting a pathogen by contacting a cell of the pathogen with an antimicrobial polymer, wherein the antimicrobial polymer comprises a polylysine structure and comprises 50% or greater functionalization with a pendent guanidium functional group.
A method, comprising:
- administering an antimicrobial polymer to a patient afflicted by a pathogen, wherein the antimicrobial polymer comprises a polylysine structure and comprises 50% or greater functionalization with a pendent guanidium functional group;
- and
- inhibiting the pathogen as a result of the administering.
A method, comprising:
- inhibiting a pathogen by contacting a cell of the pathogen with an antimicrobial polymer, wherein the antimicrobial polymer comprises a polylysine structure functionalized with a pendent guanidinium functional group, and wherein the antimicrobial polymer is comprised within a coacervate complex that further comprises an anionic polymer.
Dependencies are inferred from the claim text.