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AssigneeBausch + Lomb Ireland Limited
InventorsAlok Kumar Awasthi, Kristen Rae Hovinga, Emily Abrams Gabriel, Kevin Jacob DeRyke, Jade J. Russell
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A method for preparing an ophthalmic device for slowing, inhibiting or preventing myopia progression involves contacting an ophthalmic device having one or more reactive functional groups with one or more red-light blocking compounds having one or more reactive functional groups complementary to the one or more reactive functional groups of the ophthalmic device in a basic solution for a time period sufficient to covalently bond at least one reactive functional group of the ophthalmic device with at least one reactive functional group of the one or more red-light blocking compounds. The one or more red-light blocking compounds block greater than about 5% to about 25% of red-light transmission through the ophthalmic device at a wavelength of from about 550 nanometers (nm) to about 800 nm.
A modified silicone ophthalmic device which comprises one or more red-light blocking compounds having at least one reactive functional group covalently bonded to at least one reactive functional group of an unmodified silicone ophthalmic device, wherein the one or more red-light blocking compounds block greater than about 5% to about 25% of red-light transmission through the modified ophthalmic device at a wavelength of from about 550 nanometers (nm) to about 800 nm, wherein the unmodified silicone ophthalmic device is a polymerization product of a monomeric mixture comprising one or more silicone-containing monomers or prepolymers, wherein at least one of the one or more silicone-containing monomers or prepolymers include one or more non-bulky organosilicon-containing monomers containing at least one silyl-alkyl-siloxanyl repeating unit or one or more non-bulky organosilicon-containing prepolymers containing at least one silyl-alkyl-siloxanyl repeating unit.
Dependencies are inferred from the claim text.