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US 12,552,844 B2Granted
De-epitoped alpha gliadin and use of same for the management of celiac disease and gluten sensitivity
AssigneeUkko Inc.
InventorsYanay Ofran, Moshe Ben-David, Assaf Biran, Shiri Zakin, Orly Marcu Garber, Anna Chuprin
Life of this patent
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Abstract
A de-epitoped alpha gliadin is provided. Methods of generating same and uses thereof are also provided.
Claims8
A de-epitoped alpha gliadin polypeptide mutated compared to the corresponding wild-type gliadin polypeptide, wherein the de-epitoped gliadin polypeptide comprises the amino acid sequence as set forth in any of SEQ ID NOs:
- 49-58, SEQ ID NOs:
- 62-79, or SEQ ID NO:
- 113.
Dependencies are inferred from the claim text.