Methods and compositions for targeting Tregs using CCR8 inhibitors
AssigneeNanjing Immunophage Biomedical Co., Ltd.
InventorsGuohuang Fan, Hongyu Yang, Kin Chiu Fong, Jianfei Wang
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Abstract
The present invention provides compounds of Formula (I) which can be used as CCR8 inhibitors, which can be used as treatment or prevention of cancer using CCR8 inhibitors targeted tumor specific T regulatory cells.
Claims5
A compound or a pharmaceutically acceptable salt, isotope, stereoisomer, tautomer, solvate, or combination thereof, wherein the compound is selected from the group consisting of:
A compound or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof, wherein the compound is
A compound or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof, wherein the compound is
A compound or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof, wherein the compound is
Dependencies are inferred from the claim text.