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US 12,551,511 B2Granted
Methods to differentiate stem cells into hormone-producing cells
AssigneeJangoBio, LLC
InventorsCraig S. Atwood, Sivan Vadakkadath Meethal
Life of this patent
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Abstract
Methods are described for differentiating stem and post-natal cells into sex hormone-producing cells that can be administered to a patient autologously or allogeneically in order to maintain in balance, or rebalance, their hypothalamic-pituitary-gonadal (HPG) axis.
Claims23
A method of differentiating cells, the method comprising:
- incubating stem cells with one or more of RJW, PE, E2, DPN, 4-HP, and RSV to induce the stem cells to differentiate into gonadal hormone-producing cells, wherein the stem cells are selected from Mesenchymal stem cells (MSC) and induced pluripotent stem cells (iPS cells) and wherein the stem cells are differentiated into male-specific hormone-producing cell types or female-specific hormone-producing cell types.
Dependencies are inferred from the claim text.