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US 12,551,203 B2Granted
Catheter with vessel lining for cell collection and methods for using same
AssigneeCellapax Corporation
InventorsAlbert K. Chin, Michael Glennon
Life of this patent
Estimating the term…
Abstract
A system and method for cell collection within a vessel. The system including a cannula having a pathway extending from a first end to a second end, a elongated member situated longitudinally within the pathway of the cannula, a sleeve coupled to the second end of the cannula and a balloon situated within the sleeve.
Claims21
A system for cell collection within a vessel, the system comprising:
- a cannula having a pathway extending between a first end and a second end of the cannula;
- an elongated member situated longitudinally within the pathway of the cannula, the elongated member includes a conduit having a longitudinal axis and a distal end;
- a balloon situated within the cannula and being coupled at one end to the distal end of the elongated member to permit a device to extend longitudinally though the conduit and a distal end of the balloon, and coupled at an opposing end to the second end of the cannula to permit eversion of the balloon when the elongated member is advanced, wherein the balloon has a pathway extending from the elongated member to a distal end of the balloon when the balloon is everted and inverted;
- a sleeve situated within the balloon and being affixed at one end adjacent to the second end of the cannula to permit eversion and inversion of the sleeve, such that (i) when the balloon is completely everted from the cannula, the sleeve is everted, the sleeve is detached from the balloon along the length of the balloon, and is positioned over an expanded portion of the balloon, when the balloon is everted, such that the sleeve collects cells, and (ii) when the cannula is withdrawn from the vessel, the sleeve moves and is withdrawn with the cannula;
- and
- a sheath co-axial with the cannula and disposed on an exterior of the cannula, the sheath being configured to be advanced distally over the sleeve to protect cell samples collected by sleeve, while the sleeve is in an inverted and everted configuration.
3 more elements
A method for cell collection within a vessel, the method comprising:
- placing a cannula within the vessel within a body, the cannula comprising:
- a pathway extending between a first end and a second end of the cannula;
- an elongated member situated longitudinally within the pathway of the cannula, and having a conduit having a longitudinal axis and a distal end;
- a balloon situated within the cannula and being coupled at one end to the distal end of the elongated member, to permit a device to extend longitudinally though the conduit and a distal end of the balloon, and coupled at an opposing end to the second end of the cannula, wherein the balloon has a pathway extending from the elongated member to a distal end of the balloon when the balloon is everted and inverted;
- a sleeve situated within the balloon and being attached at one end adjacent to the second end of the cannula, such that upon eversion of the balloon from the cannula, the sleeve is everted from within the cannula to evert the sleeve out the second end of the cannula such that the sleeve is detached from the balloon along the length of the balloon and is positioned over an expanded portion of the balloon, when the balloon is everted;
- and
- a sheath co-axial with the cannula and disposed on an exterior of the cannula, the sheath being configured to be advanced distally over the sleeve, while the sleeve is in the inverted and the everted configuration;
- allowing a fully everted balloon to apply pressure to the sleeve against the vessel, such that the sleeve collects sample cells on a surface of the sleeve;
- and
- withdrawing the cannula, including the sleeve, from within the vessel within the body, while at least a portion of the sheath protects cell samples collected on sleeve.
7 more elements
Dependencies are inferred from the claim text.