Pathological section analyzer with large field of view, high throughput and high resolution

A pathological section analyzer, comprising:

• an image collector, a data preprocessing circuit, an image super-resolution circuit and an image analysis circuit;
• wherein a use process of the pathological section analyzer comprises:
• step 1, obtaining an unstained pathological section sample from clinic;
• step 2, collecting computing microscopic images of the pathological section sample in step 1 at different heights by using the image collector;
• step 3, inputting the computing microscopic images at the different heights in step 2 into the data preprocessing circuit to obtain a low-resolution reconstructed image after twin images are removed;
• step 4, inputting the low-resolution reconstructed image in step 3 into the image super-resolution circuit to obtain a high-resolution reconstructed image;
• and
• step 5, inputting the high-resolution reconstructed image in step 4 into the image analysis circuit to obtain an auxiliary diagnosis result of the pathological section sample in step 1;
• wherein the image super-resolution circuit is configured to perform the following steps:
• step 41, cropping the low-resolution reconstructed image into image patches with a size of 512*512 pixels in a fixed order, with lengths and widths overlapping by ⅔ pixels;
• step 42, inputting the image patches in step 41 into a pre-trained super-resolution model to obtain high-resolution image patches;
• step 43, replacing pixel values of ⅓ areas at boundaries of the left and right adjacent high-resolution image patches with pixel values of a ⅓ length or width area at a middle of the high-resolution image patch to eliminate boundary blur caused by truncation effect;
• step 44, recovering the high-resolution image patches without the boundary blur obtained in step 43 into the high-resolution reconstructed image according to the fixed order in step 41, and thereby realizing super-resolution of the low-resolution reconstructed image;
• wherein the high-resolution reconstruction image is also referred to as a whole slide image (WSI) in clinical electronic scanning.