Method and system for evaluation of drug concentration in blood, plasma or serum

A method for evaluating a pharmaceutical concentration in body fluid samples taken from a patient during treatment of the patient with the pharmaceutical, wherein the pharmaceutical comprises an antibiotic or cytostatic, and wherein said body fluid samples are blood, plasma or serum, said method comprising the steps of:

• preparing at least one body fluid sample comprising the pharmaceutical in a solved state by
• diluting the body fluid sample by adding a volume of clean water or saline which is at least 50% of the body fluid sample volume;
• and
• removing unsolved components from the body fluid sample;
• performing absorption spectrophotometric analysis on the at least one body fluid sample using UV-VIS light with wavelengths between 200-800 nm;
• evaluating a concentration of the pharmaceutical in the at least one body fluid sample based on the spectrophotometric analysis, wherein the step of evaluating the concentration in the body fluid sample comprises comparing the spectrophotometric analysis with pre-stored spectrophotometric spectra for the pharmaceutical at different concentrations and with a patient reference spectra,
• wherein the patient reference spectra is a spectrophotometric spectra for at least one body fluid sample from the patient taken before a start of the treatment or in the beginning of the treatment of the patient with the pharmaceutical.