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US 12,545,636 B2Granted
Acyclic lipids and methods of use thereof
AssigneeReNAgade Therapeutics Management Inc.
InventorsMuthusamy Jayaraman, Stephen Scully
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Abstract
The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
Claims17
A compound selected from the group consisting of
- Structure
- Cpd.
- 68
- or a pharmaceutically acceptable salt thereof.
1 more element
A lipid nanoparticle (LNP) comprising an ionizable lipid selected from the group consisting of
- Structure
- Cpd.
- 68
- or a pharmaceutically acceptable salt thereof.
1 more element
A lipid nanoparticle (LNP) comprising:
- (A) an ionizable lipid selected from the group consisting of:
- Structure
- Cpd.
- 68
- or a pharmaceutically acceptable salt thereof;
- an
- (B) a coding RNA.
4 more elements
Dependencies are inferred from the claim text.