Method for manufacturing oxygenator
AssigneeTerumo Kabushiki Kaisha
InventorsRenjo Takama, Takeshi Sato
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Abstract
A coating layer containing a silicone compound is formed on an inner surface of a hollow fiber membrane for manufacturing an oxygenator having a plurality of porous hollow fiber membranes for gas exchange. The method includes dissolving a silicone compound in an organic solvent having a surface tension of less than 70 dyn/cm to prepare a coating solution; and bringing an inner surface of the hollow fiber membranes into contact with the coating solution while bringing an outer surface of the hollow fiber membranes into contact with water to form a coating layer containing a silicone compound on the inner surface.
Claims16
A method for manufacturing an oxygenator having a plurality of porous hollow fiber membranes for gas exchange, comprising the steps of:
- dissolving a silicone compound in an organic solvent having a surface tension of less than 70 dyn/cm to prepare a coating solution;
- and
- bringing an inner surface of the hollow fiber membranes into contact with the coating solution while bringing an outer surface of the hollow fiber membranes into contact with water to form a coating layer containing a silicone compound on the inner surface.
A method for manufacturing an oxygenator having a plurality of porous hollow fiber membranes for gas exchange, comprising the steps of:
- fixing ends of the hollow fiber membranes to partition walls at opposing ends of a housing such that the ends of the hollow fiber membranes are open, wherein the housing defines a gas chamber inside the hollow fiber membranes and a blood chamber outside the hollow fiber membranes;
- dissolving a silicone compound in an organic solvent to prepare a coating solution;
- filling the blood chamber with water to bring outer surfaces of the hollow fiber membranes into contact with the water;
- filling the gas chamber with the coating solution to bring inner surfaces of the hollow fiber membranes into contact with the coating solution while the water contacts the outer surfaces to form a coating layer containing a silicone compound on the inner surfaces;
- removing the coating solution from the gas chamber;
- and
- removing the water from the blood chamber.
Dependencies are inferred from the claim text.