Internal dose-adapted automated external beam radiation therapy
AssigneeVarian Medical Systems, Inc.
InventorsDebanti Sengupta, Patrick Kupelian, Ryan Clark, Luca Cozzi, Donald Hoang
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Abstract
Systems, devices and methods for internal dose adapted automated external radiation beam therapy, and systems and methods for an automated adaptive workflow to automatically generate a radiation treatment plan based on the internal dose and adapt the treatment plan to a current treatment session using a set of directives.
Claims36
A radiation treatment method, comprising:
- exposing a patient to a dual modality radiation protocol, the dual modality radiation protocol including:
- an internal radiation protocol;
- and
- an external beam radiation protocol,
- the internal radiation protocol including:
- administering a radiopharmaceutical to the patient;
- and
- generating a dosimetric image of a distribution of a radiopharmaceutical activity within the patient;
- and
- the external beam radiation protocol including implementing an automated workflow to:
- generate a radiation treatment plan based on dosimetric image data;
- adapt the radiation treatment plan for a current treatment session using a set of directives;
- and
- deliver the adapted treatment plan to the patient.
A method for generating a treatment plan for an external beam radiation therapy, comprising:
- obtaining a dosimetric SPECT/CT or PET/CT image from an internal radiation treatment system indicating a radiopharmaceutical uptake within a patient;
- automatically converting the radiopharmaceutical uptake into targets to be irradiated and targets to be avoided;
- applying an automated contouring process to generate target structures on a reference image, the target structures representing contours of the targets to be irradiated and contours of the targets to be avoided, the reference image being a CT image used to obtain the dosimetric SPECT/CT or PET/CT image;
- and
- selecting a set of planned clinical goals for the target structures as an input to a plan generation and optimization algorithm to automatically derive objectives for the set of planned clinical goals and generate a reference treatment plan that fulfills the derived objectives.
A system for implementing an automated workflow for an adaptive radiation therapy session of a patient, comprising:
- a computer processing system configured to:
- obtain a set of directives, the set of directives including information representing a planned treatment plan for the patient;
- and
- using the set of directives, perform a series of automated steps to:
- generate a treatment session patient model;
- and
- generate an adapted treatment plan for the treatment session patient model,
- wherein the planned treatment plan is generated based on dosimetric image data obtained in an internal radiation treatment protocol, the dosimetric image data indicating a radiopharmaceutical uptake within the patient.
Dependencies are inferred from the claim text.