Method for preparing a haemostatic composition
AssigneesEthicon, Inc., Ferrosan Medical Devices A/S
InventorsPeter Lund Hammershøj, Kristian Larsen, Douglas B. Johns, Nicole Smith, Michael Cardinale, Gabriella Ferrara, Guanghui Zhang
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Abstract
The present disclosure relates to a method for preparing a haemostatic composition comprising thrombin, the method comprising the step of reconstituting a dry thrombin directly in a paste, such as a paste comprising a biocompatible polymer. The haemostatic composition comprising thrombin may be prepared from a dry thrombin composition and a paste in a single step operation and be used for treatment of a wound.
Claims24
A method of preparing a haemostatic composition having a substantially homogenous distribution of thrombin, the method comprising:
- a) providing a dry thrombin composition in a first syringe;
- b) providing a paste comprising a biocompatible polymer in a second syringe, wherein the paste comprises the biocompatible polymer in a content of 7% w/w to 20% w/w;
- c) connecting the first syringe and the second syringe using a suitable connector;
- and
- d) transferring the contents of the syringes back and forth between the connected syringes to achieve a substantially homogenous distribution of thrombin in the haemostatic composition.
A kit for preparing a haemostatic paste having a substantially homogenous distribution of thrombin, comprising:
- a) a first syringe comprising a dry thrombin composition;
- b) a second syringe comprising a paste comprising a biocompatible polymer, wherein the paste comprises the biocompatible polymer in a content of 7% w/w to 20% w/w;
- c) optionally an outer package;
- and
- d) instructions for using the kit for preparing a haemostatic paste,
- wherein the two syringes are interconnectable to allow for transferring the contents between the syringes.
Dependencies are inferred from the claim text.