Methods for preventing and treating brain inflammation
AssigneeBioxodes
InventorsStéphanie Demoulin, Valérie Pireaux, Edmond Godfroid
Life of this patent
Estimating the term…
Abstract
Methods for treating brain inflammation, including brain inflammation occurring or susceptible to occur after brain hemorrhage, which include the administration of a protein or polypeptide including a polypeptide having at least 75% sequence identity with the amino acid sequence SEQ ID NO: 1, or a pharmaceutical composition including the protein or polypeptide. Also, a method for preventing, reducing, decreasing, and/or inhibiting neuronal death, which includes the administration of a protein or polypeptide including a polypeptide having at least 75% sequence identity with the amino acid sequence SEQ ID NO: 1, or a pharmaceutical composition including the protein or polypeptide.
Claims16
A method for treating brain inflammation occurring after an onset of a brain hemorrhage in a subject, comprising administering to said subject after the onset of the brain hemorrhage, a therapeutically effective amount of a protein or polypeptide comprising a polypeptide having at least 90% sequence identity with the amino acid sequence SEQ ID NO:
- 1, or a pharmaceutical composition comprising thereof, wherein said protein or polypeptide is administered within 120 hours after the onset of brain hemorrhage in said subject, wherein said brain inflammation occurs after the onset of the brain hemorrhage, and wherein said brain inflammation is not induced by the presence or the formation of a thrombus.
A method for treating brain inflammation occurring after an onset of a brain injury in a subject, comprising administering to said subject after the onset of the brain injury a therapeutically effective amount of a protein or polypeptide comprising a polypeptide having at least 90% sequence identity with the amino acid sequence SEQ ID NO:
- 1, or a pharmaceutical composition comprising thereof, wherein said protein or polypeptide is administered within about 120 hours after the onset of brain injury, wherein said brain inflammation occurs after the onset of the brain injury, and wherein said brain inflammation is not induced by the presence or the formation of a thrombus.
Dependencies are inferred from the claim text.