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US 12,544,413 B2Granted
Composition with antibacterial and re-epithelializing action including probiotics
AssigneeEos2021 S.R.L.
InventorGino Santini
Life of this patent
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Abstract
The present invention relates to the strain of Lactobacillus plantarum NCIMB 43029, the strain of Lactobacillus acidophilus NCIMB 43030, a composition with both antibacterial and re-epithelializing action which includes Lactobacillus plantarum and Lactobacillus acidophilus and optionally Streptococcus thermophilus and/or Bacillus amyloliquefaciens intended to be used as a medicament for the re-epithelialisation of lesions or wounds, a bandage comprising said composition and kits comprising such a composition.
Claims10
A medicine or medicament comprising:
- (a) a bacterial combination comprising:
- (i) a Lactobacillus plantarum;
- (ii) a Lactobacillus acidophilus strain;
- (iii) a Streptococcus thermophilus strain;
- or combination thereof, and
- (b) a Bacillus amyloliquefaciens comprising a 16S rRNA as encoded by SEQ ID NO:
- 10,
- wherein the Lactobacillus plantarum comprises:
- (1) a Lactobacillus plantarum strain with accession number NCIMB 43029, or
- (2) a Lactobacillus plantarum strain comprising the hyper variable regions V1-V3 of a gene encoding for 16S rRNA of SEQ ID NO:
- 4, a groEL gene of SEQ ID NO:
- 5 and a pheS gene of SEQ ID NO:
- 6, and
- wherein the Lactobacillus acidophilus strain comprises:
- (1) a Lactobacillus acidophilus strain with accession number NCIMB 43030, or
- (2) a Lactobacillus acidophilus strain comprising the hyper variable regions V1-V3 of a gene encoding for the 16S rRNA of SEQ ID NO:
- 1, a groEL gene of SEQ ID NO:
- 2 and a pheS gene of SEQ ID NO:3,
- wherein the Streptococcus thermophilus strain comprises the hyper variable regions V1-V2 of a gene encoding for the 16S rRNA of SEQ ID NO:
- 7, a recA gene of SEQ ID NO:
- 8 and a secA gene of SEQ ID NO:
- 9.
19 more elements
Dependencies are inferred from the claim text.