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US 12,544,225 B2Granted
Systems and methods for heart valve therapy
AssigneeCaisson Interventional, LLC
InventorsKavitha Ganesan, Ramji Iyer, Lucas T. Schneider, Todd J. Mortier, Cyril J. Schweich, Jr.
Life of this patent
Estimating the term…
Abstract
Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Deployment systems and methods for using the deployment systems described herein facilitate implanting a two-part prosthetic heart valve that is arranged in a nested configuration during the transcatheter delivery and deployment processes.
Claims20
A transcatheter mitral valve replacement system for a heart, comprising:
- a delivery sheath having a distal end portion insertable into a left atrium;
- a delivery catheter slidably disposed within the delivery sheath, the delivery catheter defining an end luminal orifice and at least one non-end luminal orifice;
- and
- a two-part prosthetic mitral valve coupled to the delivery catheter by one or more control wires, the two-part prosthetic mitral valve configured to be disposed within the delivery sheath in a radially compressed condition and to radially self-expand when the two-part prosthetic mitral valve is outside of the delivery sheath and is unconstrained by the one or more control wires, the two-part prosthetic mitral valve comprising:
- a valve assembly including an expandable valve frame and a tri-leaflet occluder;
- and
- an anchor assembly separately expandable from the valve assembly and defining an interior space within which the valve assembly is nested while the two-part prosthetic mitral valve is within the delivery sheath for simultaneous deployment from the delivery sheath, the anchor assembly comprising a supra-annular engagement feature and a sub-annular engagement feature,
- wherein the valve assembly and the anchor assembly are separable from one another, such that the valve assembly and the anchor assembly are separable valve and anchor assemblies simultaneously coupled to the delivery catheter by the one or more control wires while the valve assembly is nested in the anchor assembly, and
- wherein the one or more control wires includes a first control wire coupled to a proximal end portion of the anchor assembly and extending through the at least one non-end luminal orifice, a second control wire coupled to a mid-body portion of the anchor assembly, and a third control wire coupled to the valve assembly extending through the end luminal orifice, the first control wire operable to control a position of the supra-annular engagement feature, and the second control wire operable to control a position of the sub-annular engagement feature independent of the supra-annular engagement feature.
6 more elements
A transcatheter mitral valve replacement system for a heart, comprising:
- a delivery sheath having a distal end portion insertable into a left atrium;
- a delivery catheter slidably disposed within the delivery sheath, the delivery catheter defining an end luminal orifice and at least one non-end luminal orifice;
- and
- a two-part prosthetic mitral valve coupled to the delivery catheter by one or more control wires, the two-part prosthetic mitral valve configured to be disposed within the delivery sheath in a radially compressed condition and to radially self-expand when the two-part prosthetic mitral valve is outside of the delivery sheath and is unconstrained by the one or more control wires, the two-part prosthetic mitral valve comprising:
- a valve assembly including an expandable valve frame and a tri-leaflet occluder;
- an anchor assembly separately expandable from the valve assembly and defining an interior space within which the valve assembly is nested while the two-part prosthetic mitral valve is within the delivery sheath for simultaneous deployment from the delivery sheath, wherein the valve assembly and the anchor assembly are separable from one another, such that the valve assembly and the anchor assembly are separable valve and anchor assemblies simultaneously coupled to the delivery catheter by the one or more control wires while the valve assembly is nested in the anchor assembly;
- and
- wherein the one or more control wires includes a first portion of control wires coupled to the valve assembly and a second portion of control wires coupled to the anchor assembly, and the first portion of control wires includes a first control wire and a second control wire, the second control wire extending through the end luminal orifice, the second portion of control wires includes a third control wire generally axially aligned with the first control wire and a fourth control wire axially offset from the first control wire and the second control wire, and the fourth control wire extending through the at least one non-end luminal orifice.
5 more elements
Dependencies are inferred from the claim text.