Biomechanical measurement devices and uses thereof for phenotype-guided movement assessment, intervention, and active assistance device control
AssigneesTrustees of Boston University, President and Fellows of Harvard College
InventorsLouis Awad, Dheepak Arumukhom Revi, Conor Walsh, Stefano Marco Maria De Rossi
Life of this patent
Estimating the term…
Abstract
Systems, devices, and methods described herein may involve receiving movement data associated with a subject, the movement data collected during repetitive movement of the subject; generating a phase portrait based on the movement data; calculating a phase portrait metric of a characteristic of the phase portrait; and assigning the subject to a movement phenotype based on the phase portrait metric.
Claims21
A method of phenotype-guided movement assessment, comprising:
- receiving movement data associated with a subject, the movement data collected during repetitive movement of the subject, the repetitive movement comprising ambulation including at least one stride;
- generating a phase portrait defining a substantially circular orbit based on the movement data associated with the at least one stride;
- calculating a phase portrait metric of a characteristic of the phase portrait, wherein calculating the phase portrait metric comprises calculating an amplitude for each stride of the repetitive movement based on an average polar radius of the substantially circular orbit of the phase portrait for each stride, and calculating an average amplitude for the repetitive movement based on the amplitude of each stride;
- assigning the subject to a movement phenotype based on the phase portrait metric;
- guiding application of a treatment to the subject based on the assigned movement phenotype, wherein the treatment comprises applying gait training to the subject with an assigned movement phenotype based on the average amplitude for the repetitive movement;
- and
- applying the treatment to the subject based on the assigned movement phenotype, the treatment comprising applying the gait training using at least one of a robotic exosuit, a neuroprosthesis, or a Rhythmic Auditory Stimulation (RAS) device.
A system of phenotype-guided movement assessment, comprising:
- an assistive device;
- a sensor configured to collect movement data associated with a subject during repetitive movement of the subject, the repetitive movement comprising ambulation including at least one stride;
- and
- a processor operationally coupled to the sensor, the processor configured to:
- receive movement data associated with the subject from the sensor, the movement data collected during the repetitive movement of the subject;
- generate a phase portrait defining a substantially circular orbit based on the movement data associated with the at least one stride;
- calculate a phase portrait metric of a characteristic of the phase portrait, wherein calculating the phase portrait metric comprises calculating an amplitude for each stride of the repetitive movement based on an average polar radius of the substantially circular orbit of the phase portrait for each stride, and calculating an average amplitude for the repetitive movement based on the amplitude of each stride;
- assign the subject to a movement phenotype based on the phase portrait metric,
- wherein the processor is configured to instruct the assistive device to apply a treatment to the subject based on the assigned movement phenotype, wherein the treatment comprises applying gait training to the subject with an assigned movement phenotype based on the average amplitude for the repetitive movement.
Dependencies are inferred from the claim text.