Split flow modulator for comprehensive two-dimensional chromatography
AssigneeLeco Corporation
InventorLeonid M. Blumberg
Life of this patent
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Abstract
A re-sampling device for two-dimensional gas chromatography includes a modulator and at least one of a first splitter disposed upstream from the modulator and configured to split an effluent from a primary column and deliver a portion of the effluent to waste and a portion of the effluent to the modulator, or a second splitter disposed downstream from the modulator and configured to split the effluent to deliver a portion of the effluent to waste and a portion of the effluent to a secondary column.
Claims18
A device for two-dimensional gas chromatography comprising:
- a primary column;
- a secondary column downstream from the primary column;
- and
- a re-sampling device disposed between the primary column and the secondary column, the re-sampling device including:
- a modulator;
- a first splitter disposed upstream from the modulator and configured to split an effluent and deliver a portion of the effluent to waste and a portion of the effluent to the modulator;
- a second splitter disposed downstream from the modulator and configured to split the effluent to deliver a portion of the effluent to waste and a portion of the effluent to the secondary column;
- a first accumulating loop;
- a second accumulating loop;
- a first switch configured to selectively deliver the effluent from the first splitter to one of the first accumulating loop or the second accumulating loop;
- and
- a second switch configured to selectively deliver the effluent from the one of the first accumulating loop or the second accumulating loop to the second splitter.
A re-sampling device for two-dimensional gas chromatography, the re-sampling device comprising:
- a modulator;
- a first splitter disposed upstream from the modulator and configured to split an effluent from a primary column and deliver a portion of the effluent to waste and a portion of the effluent to the modulator;
- a second splitter disposed downstream from the modulator and configured to split the effluent to deliver a portion of the effluent to waste and a portion of the effluent to a secondary column;
- a first accumulating loop;
- a second accumulating loop;
- a first switch configured to selectively deliver the effluent from the first splitter to one of the first accumulating loop or the second accumulating loop;
- and
- a second switch configured to selectively deliver the effluent from the one of the first accumulating loop or the second accumulating loop to the second splitter.
Dependencies are inferred from the claim text.