US 12,540,336 B2Granted

Lentiviral vector transfer plasmid and methods of use

AssigneeThe Medical College of Wisconsin, Inc.

InventorsJeffrey A. Medin, William M. McKillop, Kristy J. Gargulak

Life of this patent

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The present invention provides an improved lentiviral backbone for use in gene therapy.

Dependent claims

A lentiviral polynucleotide backbone having a sequence with at least 90% similarity to SEQ ID NO:

1, wherein the backbone comprises a multiple cloning site that allows for the insertion of a transgene of interest.

Dependencies are inferred from the claim text.

C12N 15/86
For animal cells: viral vectors
C12N 15/65
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression: using markers
C12N 2740/16043
Use of virus, viral particle or viral elements as a vector: viral genome or elements thereof as genetic vector
C12N
Microorganisms or enzymes

From the US filing history. Foreign family members aren’t listed.

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