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US 12,540,123 B2Granted
Process for preparing isoindolinone derivative, novel intermediates used for the process, and a process for preparing the intermediates
AssigneeCng Bio Co., Ltd.
InventorsJae-kyung Jung, Mi Kyeong Lee, Vishwanath Manjunatha, Dae-Hee Lee, Jae-Kang Lee
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Abstract
The present invention relates to a process for preparing an isoindolinone derivative represented by Formula 1, novel intermediates used for the process and a process for preparing the intermediates.
Claims14
A compound selected from the group consisting of Formula 2, Formula 3, Formula 4, and Formula 5 below:
A process for preparing a compound of Formula 1 below, comprising
- (a) a step of preparing a compound of Formula 2 below by reacting a methyl 3-hydroxy-5-methoxybenzoate compound with phenylethylamine and formaldehyde;
- and
- (b) a step of preparing a compound of Formula 3 below by reacting the compound of Formula 2 below with an acid and then reacting with a base.
Dependencies are inferred from the claim text.