Medical device with substrate comprising natural fibres

A medical device for insertion into a natural or artificial body opening, the medical device being a catheter and comprising a substrate forming a tubular body and having a wall enclosing an internal cavity, the wall extending between a proximal insertion end and a distal rearward end, wherein said wall comprises at least 30 wt % of natural fibers wherein the substrate is provided with a hydrophilic coating, the hydrophilic coating providing a low-friction surface character to the medical device when wetted by a wetting fluid, wherein the substrate is formed of at least two layers including an inner layer and an outer layer, wherein the inner layer has a Cobb value and the outer layer has a Cobb value that is higher than the inner layer, wherein the Cobb value of the inner layer is between 10-30 g/m2 and the Cobb value of the outer layer is between 100-150 g/m2.