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US 12,539,352 B2Granted
Frozen, porous thin films and methods of making and use thereof
AssigneeUniversity of Central Florida Research Foundation, Inc.
InventorsStephen J. Florczyk, Kailei Xu
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Abstract
Frozen, porous thin films and methods of making and use thereof are described herein. The frozen, porous thin films can comprise a continuous phase permeated by a plurality of pores; wherein the continuous phase comprises a polymer, a ceramic material, or a combination thereof. In some examples, the frozen, porous thin films are made by freeze casting.
Claims18
A cell culture substrate or platform comprising a frozen, porous thin film comprising:
- a continuous phase permeated by a plurality of pores;
- wherein the continuous phase comprises a polymer, a ceramic material, or a combination thereof;
- wherein the plurality of pores have an average pore size of from 1 micrometer (μm) to 200 μm;
- wherein the frozen, porous thin film has an average thickness of from 1 μm to 100 μm;
- and
- wherein the frozen, porous thin film provides improved cell seeding, cell growth, cell recovery, cell imaging, or a combination thereof relative to a similar film with a thickness greater than 100 μm.
3 more elements
Dependencies are inferred from the claim text.