Nanocomposite particle and uses thereof

A nanocomposite particle comprising,

• a core-shell-shell nanoparticle comprising,
• a phosphor core, which is made of a first phosphor material doped with an emitter ion;
• an inner shell layer encapsulating the phosphor core, wherein the inner shell layer is made of a second phosphor material doped with an absorber ion;
• an outer shell layer encapsulating the inner shell layer, wherein the outer shell layer is made of a third phosphor material;
• and
• a cationic polymer coupled to the outer shell layer;
• an encapsulated nanorod comprising,
• a nanorod;
• and
• a mesoporous scaffold encapsulating the nanorod, in which the mesoporous scaffold comprises a therapeutic agent therein;
• wherein the encapsulated nanorod is linked with the core-shell-shell nanoparticle via an electrostatic interaction between the cationic polymer and the mesoporous scaffold;
• and
• a lipid layer encapsulating the core-shell-shell nanoparticle and the encapsulated nanorod.