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US 12,538,898 B2Granted
Animal cage-sample collection apparatus
AssigneeIDEXX Laboratories, Inc.
InventorsMatthew H. Myles, Marcus J. Crim, Robert S. Livingston, Cynthia L. Besch-Williford, Kristin S. Riley
Life of this patent
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Abstract
Apparatuses, systems, and methods for the collection and sampling of agents (including organisms and pathogens) to determine the health of an animal colony. A collection media is configured to collect a sample from a target animal, such as a mouse or rat. The collected sample may include dust, feces, fur, urine, saliva, or other aspect of the target animal's environment.
Claims7
A method of monitoring animal health, comprising:
- introducing a cage sample collection apparatus comprising a collection media in an animal cage;
- collecting an environmental sample from the cage on the cage sample collection media, wherein the environmental sample comprises at least one of dust, feces, fur, urine, and saliva;
- removing at least a portion of the collection media from the animal cage;
- and
- analyzing the collection media for the presence of an agent or a marker for the agent, wherein the animal cage houses at least one of:
- a mouse and wherein analyzing the collection media comprises analyzing for the presence or absence of seven or more agents selected from the group consisting of:
- a. Mouse Hepatitis Virus (MHV);
- b. Minute Virus of Mice (MVN);
- c. NS1 (Generic Parvovirus);
- d. Mouse Pneumonia Virus (MPV);
- e. Mouse Norovirus (MNV);
- f. Theiler's encephalomyelitis virus (TMEV);
- g. Mouse Group A rotavirus/Epizootic Diarrhea of Infant Mice (EDIM);
- h. Sendai virus;
- i. Mycoplasma pulmonis;
- j. Pneumonia Virus of Mice (PVM);
- k. Reovirus Type 3 (REO3);
- l. Lymphocytic Choriomeningitis (LCMV);
- m. Ectromelia virus;
- n. Murine adenovirus 1 (MAD1);
- o. Murine adenovirus 2 (MAD2);
- p. Polyoma virus;
- q. Encephalitozoon cuniculi;
- r. Filobacterium rodentium, aka. Cilia-Associated Respiratory Bacillus (CARB);
- s. Clostridium piliforme;
- t. Mouse Cytomegalovirus (MCMV);
- u. K virus;
- v. Hantaan virus;
- w. Lactate dehydrogenase-elevating virus;
- x. Mouse Thymic Virus (MTV);
- y. Helicobacter ganmani;
- z. Helicobacter mastomyrinus;
- aa. Helicobacter spp. (generic assay, detects all Helicobacter spp.);
- bb. Mycoplasma pulmonis;
- cc Pasteurella pneumotropica biotype Heyl;
- dd. Pasteurella pneumotropica biotype Jawetz;
- ee. Entamoeba muris;
- ff. Spironucleus muris;
- gg. Tritrichomonas muris;
- hh. Aspiculuris tetraptera;
- ii. Syphacia obvoleta;
- jj. Pinworm (generic assay, detects both Aspiculuris tetrapter and Syphacia obvoleta);
- kk. Myocoptes musculinus;
- ll. Helicobacter bilis;
- mm. Helicobacter hepaticus;
- nn. Helicobacter rodentium;
- oo. Helicobacter typhlonius;
- pp. Radfordia affinis/Radfordia ensiphora/Myobia musculi;
- qq. Corynebacterium bovis;
- rr. Corynebacterium sp. (Hyperkeratosis-associated Corynebacterium 2, HAC2);
- ss. Klebsiella pneumoniae;
- tt. Klebsiella oxytoca;
- uu. Staphylococcus aureus;
- vv. Staphylococcus xylosis;
- ww. Citrobacter rodentium;
- xx. Pseudomonas aeruginosa;
- yy. Clostridium piliforme;
- zz. Clostridium difficile;
- aaa. Bordetella bronchiseptica;
- bbb. Bordetella hinzii;
- ccc. Bordetella pseudohinzii;
- ddd. Proteus mirabilis;
- eee. Proteus spp.;
- fff. Salmonella spp.;
- ggg. Salmonella enterica;
- hhh. Pneumocystis murina;
- iii. Murine Astrovirus;
- jjj. Giardia spp.;
- kkk. Demodex musculi;
- lll. Cryptosporidium spp.;
- mmm. Eimeria spp.;
- nnn. Ornithonyssus spp.;
- and
- ooo. Rodentolepis nana;
- or
- a rat, and wherein the step of analyzing the collection media comprises analyzing for the presence or absence of seven or more infectious agents selected from the group consisting of:
- a. Rat Coronavirus (RCV);
- b. NS1 (Generic Parvovirus);
- c. Rat Parvovirus 1 (RPV-1);
- d. Rat Parvovirus 2 (RPV-2);
- e. Rat Minute Virus (RMV);
- f. Kilham Rat Virus (KRV);
- g. Toolan's H-1 Virus (H-1);
- h. Rat theilovirus (RTV);
- i. Sendai virus;
- j. Pneumonia Virus of Mice (PVM);
- k. Mycoplasma pulmonis;
- l. Reovirus Type 3 (REO3);
- m. Lymphocytic Choriomeningitis Virus (LCMV);
- n. Cilia-Associated Respiratory Bacillus (CARB);
- o. Hantavirus;
- p. Clostridim piliforme;
- q. Mouse Adenovirus 1 (MAD1);
- r. Mouse Adenovirus 1 (MAD2);
- s. Encephalitozoom cuniculi;
- t. Group B rotavirus of rats (IDIR);
- u. Sialodacryoadenitis Virus (SDAV);
- v. Rat Polyomavirus 2 (RPyV-2);
- w. Helicobacter bilis;
- x. Helicobacter hepaticus;
- y. Helicobacter rodentium;
- z. Helicobacter typhlonius;
- aa. Helicobacter ganmani;
- bb. Helicobacter mastomyrinus;
- cc. Helicobacter spp. (generic assay, detects all Helicobacter spp.);
- dd. Mycoplasma pulmonis;
- ee. Streptobacillus moniliformis;
- ff. Streptococcus pneumoniae;
- gg. beta-hemolytic Streptococcus spp. (not Group B);
- hh. Pasteurella pneumotropica biotype Heyl;
- ii. Pasteurella pneumotropica biotype Jawetz;
- jj. Entamoeba muris;
- kk. Spironucleus muris;
- ll. Tritrichomonas muris;
- mm. Aspiculuris tetraptera;
- nn. Syphacia muris;
- oo. Pinworm (generic assay, detects both Aspiculuris tetraptera and Syphacia muris);
- pp. Corynebacterium bovis;
- qq. Corynebacterium sp. (Hyperkeratosis-associated Corynebacterium 2, HAC2);
- rr. Corynebacterium kutscheri;
- ss. Klebsiella pneumoniae;
- tt. Klebsiella oxytoca;
- uu. Staphylococcus aureus;
- vv. Staphylococcus xylosus;
- ww. Citrobacter rodentium;
- xx. Proteus mirabilis;
- yy. Proteus spp.;
- zz. Pseudomonas aeruginosa;
- aaa. Clostridium piliforme;
- bbb. Clostridium difficile;
- ccc. Bordetella bronchiseptica;
- ddd. Bordetella hinzii;
- eee. Bordetella pseudohinzii;
- fff. Salmonella spp.;
- ggg. Salmonella enterica;
- hhh. Pneumocystis spp.;
- iii. Encephalitozoon cuniculi;
- jjj. Giardia spp.;
- kkk. Demodex spp.;
- lll. Cryptosporidium spp.;
- mmm. Eimeria spp.;
- nnn. Polyplax spp.;
- ooo. Myocoptes musculinus;
- ppp. Radfordia affinis/Radfordia ensifera/Myobia musculi;
- qqq. Ornithonyssus spp.;
- rrr. Hymenolepis spp.;
- sss. Rodentolepis nana;
- and
- ttt. Boone Cardiovirus.
146 more elements
Dependencies are inferred from the claim text.