Method and system for the amplification of a nucleic acid

A system for amplification of a nucleic acid, comprising:

• at least one local heating element functionalized with at least one connection nucleic acid bound to the local heating element within a solution containing the nucleic acid to be amplified, and
• at least one primer complementary nucleic acid configured to:
• bind to the at least one connection nucleic acid by means of an enzymatic reaction, the at least one primer complementary nucleic acid comprising (a) a primer complementary segment, and (b) a connection segment that is at least partially complementary to a nucleotide sequence of the connection nucleic acid,
• wherein the connection nucleic acid is selected such that the connection nucleic acid is configured to serve at least partially as a primer for amplification of the nucleic acid,
• wherein the connection segment of the at least one primer complementary nucleic acid is to bind to the connection nucleic acid after being placed into the solution separately from the connection nucleic acid, and the primer segment is to bind to the nucleic acid within the solution subsequent to the binding to the connection nucleic acid, and
• wherein the connection nucleic acid is a spacer sequence and the connection segment of the at least one primer complementary nucleic acid is bound to the connection nucleic acid in parallel with the connection nucleic acid.