Polyelectrolyte hydrogel coating with strong substrate binding performance and method of manufacturing the same

A method of manufacturing a polyelectrolyte hydrogel coating with strong substrate binding performance, comprising:

• 1) activating a substrate by applying oxygen plasma;
• and
• 2) dissolving a polycationic polymer, a polymeric monomer, a silane coupling agent and an initiator to obtain a precursor solution, vacuumizing the precursor solution to remove air bubbles, applying the vacuumized precursor solution to a surface of the substrate activated by the oxygen plasma, and performing an in-situ polymerization and curing process under nitrogen or rare gas atmosphere;
• wherein the polymeric monomer comprises at least one of:
• acrylamide, acrylic acid, hydroxyethyl methacrylamide, 2-acrylamido-2-methyl-1-propanesulfonic acid, polyethylene glycol (diol) diacrylate, 2-methacryloxyethyl phosphocholine, 3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propane-1-sulfonate, and 3-[[2-(methacryloyloxy)ethyl]dimethylammonium]propionate;
• the silane coupling agent has a carbon-carbon double bond functional group and comprises at least one of 3-(trimethoxymethylsilyl)propyl methacrylate, O-(methacryloyloxyethyl)-N-(triethoxysilyl propyl)carbamate, and vinyltriethoxysilane, vinyltrimethoxysilane.