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US 12,534,441 B2Granted
Tryptamine analogues
AssigneeBeckley Psytech Limited
InventorsMassimo Muratore, Amir Lotfi Moghaddam, Vinod Vishwapathi, Christopher Wong, Oliver Mcgaw
Life of this patent
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Abstract
This invention relates to pharmaceutically acceptable tryptamine analogues and salts thereof. In particular, though not exclusively, the invention relates to formulations and uses of the same as a medicament.
Claims11
A compound of Formula (I) wherein:
- R1 is selected from H or C1-6 alkyl;
- and
- R2 is CH2—CHR4—NR5R6, wherein
- R4 is selected from H or C1-6 alkyl, wherein
- R5 is selected from H or C1-6 alkyl, wherein
- R6 is:
- d)
- wherein X is a bond, Y is N, Z is O and R7 and R8 together from a bringing group CH2CH2;
- or
- e)
- wherein X is NH or O, Y is CH, Z is O and R7 and R8 are H;
- or
- f) NH(CH2)3N(CH3)2, O(CH2)OH or O(CH2)2N(CH3)2
- R3 is selected from H or L-R9, wherein
- L is selected from O, N, NH, O—O, CH2, CH2CH2, O—O—CH2CH2, CO, OCO, COO or OCONH,
- wherein
- R9 is selected from H, C1-6 alkyl, COOH, OH, COO−, O−, C6-C10 aromatic, C3-C10 heteroaromatic or heterocyclic group comprising one, two or three heteroatoms independently selected from O and N;
- and
- K is CH;
- or is a pharmaceutically acceptable salt thereof.
17 more elements
Dependencies are inferred from the claim text.