Sampling device for biological specimen

A sampling device for collecting and isolating a biological specimen from a sample or from a location, the sampling device comprising a swab tip and a support body, wherein:

• the support body has a hollow conformation with a first end, a second end opposite the first end, and one or more side walls;
• the first end is in fluid connection with an internal surface of the swab tip;
• the swab tip comprises a filter material with a pore size gradient that decreases from an external surface of the swab tip to the internal surface of the swab tip, wherein the filter material covers the first end and extends down an exterior portion of the one or more side walls of the support body;
• and
• the support body is configured to collect the sample via the swab tip, transport the sample through the pore size gradient from the external surface to the internal surface, and transport the sample from the first end towards the second end upon application of a negative pressure gradient at the second end.