Blood plasma product

A method of rehydrating a spray dried plasma unit having a spray dried plasma from donor plasma from one or more donors, comprising:

• combining an amount of Sterile Water For Injection (SWFI) with the spray dried plasma unit;
• wherein the spray dried plasma reconstitutes in a time period ranging between about 2 minutes and about 5 minutes, as measured from first touch by a user to completed reconstitution with no visible clumps, to thereby obtain a reconstituted previously spray dried plasma;
• wherein the reconstituted previously spray dried plasma has a pH ranging from about 6.7 to about 7.8;
• wherein the reconstituted previously spray dried plasma has an amount of von Willebrand Ristocetin Cofactor (VWF:RCo) ranging from about 10 to about 200 IU/dL, or an amount of von Willebrand Factor Antigen (VWF:Ag) ranging from about 50 to 200 IU/dL;
• and
• wherein the reconstituted previously spray dried plasma allows for clot formation;
• and
• wherein the mean size of the particulates, compared to the mean size of the particulates in the donor plasma, is reduced by at least 10% when measured with a cell analyzer using an electrical sensing zone method for particulates having a size ranging from about 2 microns to 60 microns.