Flexible transducer arrays with a polymer insulating layer for applying tumor treating fields (TTFields)
AssigneeNovocure GmbH
InventorsYoram Wasserman, Stas Obuchovsky, Nataliya Kuplennik
Life of this patent
Estimating the term…
Abstract
Described herein are devices for applying an alternating electric field to a living subject or an in vitro medium at a frequency between 100 kHz and 500 kHz. Also described herein are methods of using the described devices for applying an AC electric field to a target region comprising rapidly dividing cells, e.g., cells associated with a variety of disorders or conditions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
Claims23
An apparatus for applying an alternating electric field to a living subject, the apparatus comprising:
- a layer of conductive material having a skin-facing front face, the front face having an area;
- a flexible polymer layer disposed forward of the layer of conductive material and positioned against the skin-facing front face of the layer of conductive material so as to cover at least a portion of the area of the front face of the layer of conductive material, the polymer layer having a skin-facing front face;
- and
- an electrical lead positioned in electrical contact with the layer of conductive material,
- wherein the polymer layer comprises at least one polymer selected from Poly(VDF-TrFE-CTFE), Poly(VDF-TrFE-CFE), and Poly(VDF-TrFE-CFE-CTFE),
- wherein the apparatus is configured to apply the alternating electric field at a frequency between 100 kHz and 500 kHz and at a field intensity ranging from 0.1 V/cm to 10 V/cm to selectively destroy or inhibit the growth of rapidly dividing cells located within a target region of the subject.
Dependencies are inferred from the claim text.