Renal replacement therapy machine

A method, comprising:

• performing a renal replacement therapy by passing blood in an extracorporeal blood circuit through a hemofilter that performs at least one of hemodialysis and hemofiltration;
• measuring at least one blood flow property at a downstream end of the hemofilter via a flow measuring device, wherein the flow measuring device comprises at least one of a viscometer and a rheometer;
• monitoring the measured at least one blood flow property via a controller;
• controlling at least one parameter of the renal replacement therapy in response to the measured at least one blood flow property and/or in response to information the controller receives form at least one data input device in communication therewith or in response to information the controller receives from at least one operator input interface in communication therewith, wherein the at least one parameter comprises any of:
• an ultrafiltration rate;
• initiation, alteration of the rate, or termination of pre-filter replacement fluid;
• initiation, alteration of rate, or termination of post-filter replacement fluid;
• a modification of blood flow rate;
• an initiation, dose adjustment, or cessation of anticoagulation, altering or adjusting a modality of the renal replacement therapy, switching between different types of dialysate fluid, switching between different types of replacement fluid;
• or at least one parameter of an ancillary medical device in communication with the controller, or any combination thereof,
• monitoring a temperature of the blood;
• and
• adjusting the temperature of the blood in response to the measured at least one blood flow property via a thermomodulator configured to heat the blood in a heating mode and to cool the blood in a cooling mode, wherein the controller is configured to control the at least one parameter of the renal replacement therapy and to adjust the temperature of the blood, wherein controlling at least one parameter and adjusting the temperature of blood is such to maintain at least one of patency of the extracorporeal blood circuit, treatment adequacy and patient safety.