Wearable and portable device for recirculating flow dialysis

A device for the removal of toxins from a patient by dialysis, said device comprising:

• i) a carrier comprising the electronics including control software, a user-interface, actuators and sensors, which carrier is configured to actuates, controls and monitors the dialysis operation;
• ii) a replaceable cartridge with a flexible tubing configured to connect to the patient, which cartridge is connected to the carrier, said replaceable cartridge includes a reusable housing with a pump, a leakage sensor, a memory chip for cartridge identification and data storage, said replaceable cartridge further includes a purification unit held inside said replaceable cartridge, said purification unit includes a compartment for holding dialysate and a sorbent system with a particle filter, said purification unit further includes tubings, connectors, check valves;
• and
• iii) an extension set that is connected to the replaceable cartridge comprising one or more additional compartments for holding dialysate mounted in a case with a heating element, a temperature controller and a power supply for the heating element, said one or more additional compartments is connected in series to said compartment of the purification unit and configured for providing recirculating flow dialysis in series.