Back to results
US 12,533,445 B2Granted
Biodegradable porous membrane for generating scaffold-free biological assemblies
AssigneeRutgers, The State University of New Jersey
InventorsKi-Bum Lee, Letao Yang
Life of this patent
Estimating the term…
Abstract
A three dimensional scaffold for generating cell or protein assemblies. This degradable scaffold can be applied to various types of cells. Also disclosed are methods of treating a condition by implanting the protein or cell assembly prepared according to the method described herein.
Claims16
A biodegradable nano porous (BNP) membrane scaffold for forming a protein or a cell assembly, comprising a plurality of nanosheet layers consisting of ultrasonicated porous manganese dioxide (MnO2) particles having an average diameter ranging from about 200 nm to about 100 μm, wherein
- (i) the scaffold comprises pores with an average diameter ranging from about 1 μm to about 50 μm;
- and
- (ii) the particles comprise a plurality of nanosheets, wherein the nanosheets have an average lateral size ranging from about 1 nm to 1 μm, and wherein the nanosheets are assembled in random directions in the particles to form porous channels.
Dependencies are inferred from the claim text.