Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof

A method for preparing a metal nuclide-loaded carbon microsphere, CMS, comprising the following steps:

• subjecting a metal ion and an organic molecule to a first reaction in an aqueous solution to obtain a complex, wherein the organic molecule is selected from the group consisting of 5-sulfosalicylic acid, 5-nitrosalicylic acid, phthalic acid, isophthalic acid, sodium catechol-3,5-disulfonate, pyrogallol, resorcinol, 8-hydroxyquinoline-5-sulfonic acid, 2,6-pyridinedicarboxylic acid, 2-pyridinecarboxylic acid, and 1,10-phenanthroline;
• allowing a CMS to adsorb the complex, wherein the CMS is a spherical or non-spherical activated carbon product with a plurality of micropores and/or mesopores, and the metal ion is adsorbed in the plurality of micropores and/or mesopores of the CMS adsorbing the complex;
• subjecting the CMS adsorbing the complex to a first treatment to obtain a metal nuclide-loaded CMS, wherein the first treatment comprises mixing the CMS adsorbing the complex with an anion solution to allow a second reaction;
• subjecting the metal nuclide-loaded CMS to solid-liquid separation to obtain a solid then adding water for injection, and sterilizing at 121° C. for 15 min to obtain a metal nuclide-loaded CMS product for injection;
• wherein
• the metal nuclide-loaded CMS in the metal nuclide-loaded CMS product for injection has a metal nuclide dissolution rate of less than 0.1% in aqueous solution at 180° C. for 2 hours at a pressure of 1-10 MPa.