Vibrio cholerae protein for use against cancer
AssigneeLinnane Pharma AB
InventorsSun Nyunt Wai, Bernt Eric Uhlin, Aftab Nadeem, Karina Persson
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Abstract
The invention relates to a Vibrio cholerae MakA (motility associated killing factor A) protein for use in therapy, in particular in the treatment or alleviation of cancer such as colorectal cancer. The invention further relates to pharmaceutical compositions comprising a Vibrio cholerae MakA protein as an active ingredient, as well as to methods for treating or alleviating cancer, comprising administering to a subject a therapeutically effective amount a Vibrio cholerae MakA protein.
Claims13
A method of treating or alleviating cancer in a mammalian subject in need thereof, comprising administering to the subject a therapeutically effective amount of a Vibrio cholerae motility associated killing factor A (MakA) protein comprising the amino acid sequence set forth in SEQ ID NO:1 or SEQ ID NO:5, wherein the cancer is colorectal cancer.
Dependencies are inferred from the claim text.