Use of mulberry twig alkaloids in preparation of drug for treating polycystic ovarian syndrome

A method of preventing and/or treating polycystic ovarian syndrome in a subject in need thereof comprising administering to the subject a composition comprising mulberry extract, wherein:

• based on the mulberry extract, the weight content of each component is as follows:
• alkaloids
• 30% to 99%,
• polysaccharides
• 0.2% to 35%,
• flavonoids
• 0% to 2%,
• amino acids
• 0% to 30%,
• other components
• 0% to 20%;
• wherein the mulberry extract is prepared according to a method comprising the steps of:
• 1) preparing a crude extraction solution of a plant of the genus Morus comprising the steps of:
• a) crushing ramulus, cortex, or folium obtained from the plant;
• and
• b) extracting the sample with water, acidic water, alcohol, or a combination thereof;
• and
• 2) separating the crude extraction solution via a cation resin or a cation resin and an anion resin to obtain the mulberry extract.