Composite including neural retina, retinal pigment epithelial cells, and hydrogel, and method for producing same

A composite comprising a neural retina, a retinal pigment epithelial cell sheet, and a hydrogel, wherein

• the neural retina and the retinal pigment epithelial cell sheet are derived from a human pluripotent stem cell respectively;
• in the neural retina, a neural retinal layer including at least a photoreceptor layer is formed, wherein the photoreceptor layer comprises at least one or more cells selected from the group consisting of a photoreceptor cell, a photoreceptor precursor cell and a retinal precursor cell;
• a melting point of the hydrogel is from 20° C. to 40° C.;
• and
• the whole of the neural retina and the retinal pigment epithelial cell sheet is embedded in the hydrogel, tangent directions of the respective surfaces of the neural retina and the retinal pigment epithelial cell sheet are approximately parallel, an apical surface of the neural retina and an apical surface of the retinal pigment epithelial cell sheet face each other, and the neural retina and the retinal pigment epithelial cell sheet are separated by the hydrogel from each other without contact.