Culture scaffold for promoting stem cell differentiation comprising multilayer graphene film
AssigneesSeoul National University R&Db Foundation, Biographene Inc.
InventorsByung Hee Hong, Ji Yeon Ahn, Jong Bo Park, Jeong Mook Lim, Woo Sub Yang
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Abstract
Provided are a culture scaffold for promoting stem cell differentiation comprising a multilayer graphene film, a method of regulating growth and differentiation of a stem cell using the culture scaffold, and a method of preparing the culture scaffold, where the culture scaffold is capable of promoting the osteogenic differentiation of stem cells as a result of laminating a graphene film without comprising an additional substance, and it may be variously applicable to application fields of stem cells in/outside the body.
Claims3
A method of promoting the osteogenic differentiation of a mesenchymal stem cell, comprising culturing the mesenchymal stem cell on a culture scaffold,
- wherein the culture scaffold is for promoting the osteogenic differentiation of the mesenchymal stem cell, the culture scaffold comprises a multi-layer graphene film,
- wherein the multi-layer graphene film is two- to seven-layer laminated graphene formed by lamination of single-layered graphene in two to seven layers, and
- wherein the multi-layer graphene film has wrinkles having a width of 20 to 60 nm.
Dependencies are inferred from the claim text.