Administration of berberine metabolites
AssigneeAxcess Global Sciences, LLC
InventorsRyan Lowery, Jacob Wilson, Shawn Wells
Life of this patent
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Abstract
In various implementations, berberine metabolites, such as dihydroberberine and/or tetrahydroberberine, may be administered to manage blood glucose levels, increase ketone levels (e.g., blood concentration of ketones), and/or for therapeutic purposes in humans. The administration of a pharmaceutically effective amount of berberine metabolites, such as dihydroberberine, may reduce fasting blood glucose levels, improve glucose tolerance, and/or improve blood ketone response. In some implementations, berberine metabolites may be administered with one or more other compounds.
Claims18
A method for inducing or maintaining ketosis in an individual, comprising:
- orally administering a composition that comprises beta-hydroxybutyrate, wherein the beta-hydroxybutyrate comprises R-beta-hydroxybutyrate and S-beta-hydroxybutyrate and is enriched in R-beta-hydroxybutyrate relative to S-beta-hydroxybutyrate,
- wherein orally administering the composition induces or maintains ketosis in the individual.
A method for inducing or maintaining ketosis in an individual, the method comprising:
- orally administering a composition, wherein the composition comprises beta-hydroxybutyrate, wherein the beta-hydroxybutyrate comprises greater than approximately 90% R-beta-hydroxybutyrate and less than approximately 10% L-beta-hydroxybutyrate;
- and
- wherein orally administering the composition induces or maintains ketosis in the individual.
A method for inducing or maintaining ketosis in an individual, comprising:
- orally administering a composition that comprises approximately 2 g to approximately 10 g of beta-hydroxybutyrate, wherein the beta-hydroxybutyrate comprises greater than approximately 90% R-beta-hydroxybutyrate and less than approximately 10% L-beta-hydroxybutyrate,
- wherein orally administering the composition induces or maintains ketosis in the individual.
Dependencies are inferred from the claim text.