Guided renal denervation using nerve stimulation with blood pressure and renal blood velocity measurements, and associated systems, device, and methods

A system, comprising:

• a processor circuit configured for communication with an endovascular flow sensor, an endovascular pressure sensor, and an endovascular nerve stimulation device, wherein the processor circuit is configured to:
• receive first and second endovascular flow measurements obtained by the endovascular flow sensor while the endovascular flow sensor is positioned within a blood vessel of the patient;
• receive first and second endovascular pressure measurements obtained by the endovascular pressure sensor while the endovascular pressure sensor is positioned within the blood vessel;
• control the endovascular nerve stimulation device to stimulate a nerve of the patient, wherein the nerve is proximate to the blood vessel, wherein the first endovascular flow measurement and the first endovascular pressure measurement are obtained before the nerve is stimulated, wherein the second endovascular flow measurement and the second endovascular pressure measurement are obtained while the nerve is stimulated;
• determine whether the nerve is afferent or efferent based on the first and second endovascular flow measurements and the first and second endovascular pressure measurements;
• and
• provide an output to a display in communication with the processor circuit, wherein output comprises an identification, for a user, of the nerve as afferent or efferent.