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US 12,529,081 B2Granted
Composition for producing ceramide
AssigneeGenuine R&D Co., Ltd.
InventorsMasakatsu Miyanabe, Shinobu Hiraki, Xiaolin Luo, Hiroyuki Imai
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Abstract
Provided is a means for preparing a free ceramide (Cer) from a glycosyl inositol phospho ceramide (GIPC). Specifically provided is a composition for digesting a glycosyl inositol phospho ceramide (GIPC) or a glucosylceramide for producing a free ceramide, the composition comprising a mushroom self-digestion liquid or purified product thereof.
Claims6
A method for producing a free ceramide, comprising:
- homogenizing enoki mushrooms, beech mushrooms, king oyster mushrooms, or any combination thereof;
- separating the homogenate into a liquid portion and a solid portion;
- collecting the liquid portion as a mushroom self-digestion liquid;
- centrifuging the mushroom self-digestion liquid to obtain a supernatant and a pellet;
- and
- reacting the mushroom self-digestion liquid, the centrifuged supernatant, or the centrifuged pellet with a glycosyl inositol phospho ceramide (GIPC) or glycosylceramide,
- wherein enoki mushrooms are also known as enokitake and have the scientific name Flammulina velutipes, beech mushrooms are also known as shimeji and have the scientific name Lyophyllum shimeji, and king oyster mushrooms are also known as eryngii and have the scientific name Pleurotus eryngii.
4 more elements
Dependencies are inferred from the claim text.