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US 12,528,840 B2Granted
Transcription active complex targeting cancer drug from viral protein sequence
AssigneeThe Regents of the University of California
InventorsYoshihiro Izumiya, Michiko Shimoda
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Abstract
The present invention provides compositions and methods for treating a disease involving inappropriate or excessive cell proliferation or for treating an inflammatory condition or an autoimmune disease by inhibiting MYC activity in cells such as MYC-dependent cancer cells.
Claims33
A polypeptide comprising a MYC-inhibiting peptide and a heterologous amino acid sequence, wherein the MYC-inhibiting peptide comprises the amino acid sequence set forth in SEQ ID NO:4, is no more than about 100 amino acids in length, and inhibits MYC activity in a cell.
Dependencies are inferred from the claim text.