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US 12,528,774 B2Granted
Thiosemicarbazone compounds and uses thereof
AssigneeThe Regents of the University of California
InventorsCaius G. Radu, Michael E. Jung, Daniel Sun, Nagichettiar Satyamurthy, Juno Van Valkenburgh, Roy Pan, Soumya Poddar
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Abstract
Provided, inter alia, are thiosemicarbazone compounds, metal complexes of thiosemicarbazone compounds, pharmaceutical compositions, and methods for treating cancer.
Claims13
A compound of Formula (Ia), a pharmaceutically acceptable salt thereof, a metal complex thereof, or a pharmaceutically acceptable salt of a metal complex thereof:
- wherein:
- R1 is unsubstituted C1-4 alkyl;
- R2 is hydrogen or unsubstituted C1-4 alkyl;
- and
- R4, R5, and R6 are each independently hydrogen, fluorine, chlorine, bromine, iodine, —NH2, N(C1-4 alkyl)(C1-4 alkyl), wherein when R2 is H, R4-R6 are all not H.
2 more elements
Dependencies are inferred from the claim text.