Dynamically optimized evoked response sensing

A method comprising:

• controlling, by processing circuitry, stimulation generation circuitry to generate a stimulation signal, according to a set of stimulation parameters, to be delivered to target anatomy of a patient via a stimulation electrode configuration from a plurality of electrodes;
• receiving, by processing circuitry and from sensing circuitry, a sensed evoked response signal responsive to the stimulation signal, the sensing circuitry sensing the sensed evoked response signal according to a set of sensing parameters defining at least a sensing electrode configuration from the plurality of electrodes;
• determining, by the processing circuitry, that a characteristic value of at least one of an artifact or the sensed evoked response signal meets a threshold;
• and
• automatically changing, by the processing circuitry and based on the determination that the characteristic value of the at least one of the artifact or the sensed evoked response signal meets the threshold, at least one of the sensing parameters, wherein automatically changing the at least one of the sensing parameters comprises changing, by the processing circuitry, at least one sensing electrode of the sensing electrode configuration to change at least one of a) a proximity of the at least one sensing electrode to the target anatomy, b) a spacing between sensing electrodes, c) a spacing between sensing electrodes and stimulation electrodes, or d) an orientation of the at least one sensing electrode.

A non-transitory computer-readable storage medium including instructions, which, when executed, cause processing circuitry to:

• control stimulation generation circuitry to generate a stimulation signal according to a set of stimulation parameters, to be delivered to target anatomy of a patient via a stimulation electrode configuration from a plurality of electrodes;
• receive from sensing circuitry, a sensed evoked response signal responsive to the stimulation signal, the sensing circuitry sensing the sensed evoked response signal according to a set of sensing parameters defining at least a sensing electrode configuration from the plurality of electrodes;
• determine that a characteristic value of at least one of an artifact or the sensed evoked response signal meets a threshold;
• and
• automatically change, based on the determination that the characteristic value of the at least one of the artifact or the sensed evoked response signal meets the threshold, at least one of the sensing parameters, wherein to automatically change the at least one of the sensing parameters the instructions cause the processing circuitry to change at least one sensing electrode of the sensing electrode configuration to change at least one of a) a proximity of the at least one sensing electrode to the target anatomy, b) a spacing between sensing electrodes, c) a spacing between sensing electrodes and stimulation electrodes, or d) an orientation of the at least one sensing electrodes.