Bactericidal/permeability increasing protein for use in a method of immunization, preferably as an adjuvant in a method of vaccination

A method of immunization of a patient, said method comprising administering to the patient an effective amount of bactericidal/permeability-increasing Protein (BPI)-stimulated target cells,

• wherein said method comprises administering BPI as a stimulant to target cells in vitro or ex vivo, wherein said stimulated target cells are subsequently administered to said patient in vivo, wherein the target cells are dendritic cells,
• wherein BPI stimulates the dendritic cells to produce cytokines that promote lymphoid cell responses,
• wherein said immunization prevents or treats a disease selected from chronic inflammatory diseases and graft-versus-host disease (GvHD), and/or wherein said immunization treats a cancerous disease.