Peptide for use in the prevention and/or treatment of a disease caused by a virus affecting the respiratory tract
AssigneeFundacion Para El Fomento De La Investigacion Sanitaria Y Biomedica De La Comunitat Valenciana (Fisabio)
InventorsAlejandro Mira Obrador, Maria de los Desamparados Ferrer García, Paula Corell Escuin, Francisco Javier López Labrador
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Abstract
Peptides and pharmaceutical compositions comprising the same are described for use in the treatment and/or prevention of a disease caused by a virus affecting the respiratory tract, and in particular by an influenza virus or a coronavirus, among others. Additionally, a method and a kit for determining in vitro the resistance of an individual to being infected by a virus affecting the respiratory tract by determining the level of said peptides in the saliva of said individual is described.
Claims11
A method of preventing and/or treating a disease caused by a virus affecting the respiratory tract, said method comprising administering an effective amount of a peptide or administering a pharmaceutical composition comprising an effective amount of said peptide and at least one pharmaceutically acceptable excipient or carrier, to a subject in need thereof, wherein said peptide comprises a sequence selected from the group consisting of:
- SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, SEQ ID NO:
- 5, SEQ ID NO:
- 19, SEQ ID NO:
- 20, SEQ ID NO:
- 21, SEQ ID NO:
- 22, and SEQ ID NO:
- 23, wherein the virus affecting the respiratory tract is selected from the group consisting of:
- an influenza virus, a coronavirus, a syncytial virus (RSV), a rhinovirus (RVs), a parainfluenza virus (PIV), an adenovirus (ADV), a morbillivirus, and an enterovirus.
Dependencies are inferred from the claim text.