Salts/cocrystals of (R)-N-(4-chlorophenyl-2-((1S,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
AssigneeBristol-Myers Squibb Company
InventorsTamar I. Rosenbaum, Melanie Janelle Bevill
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Abstract
The present disclosure relates to amorphous and crystalline forms of (R)—N-(4-chlorophenyl)-2-((1S,4S)-4-(6-fluoro-quinolin-4-yl)cyclohexyl)propanamide and its salts/cocrystals, solvates, and/or hydrates, processes for their production, pharmaceutical compositions comprising them, and methods of treatment using them.
Claims19
Crystalline (R)—N-(4-chlorophenyl)-2-((1S,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide hydrochloride salt monohydrate Form A, having one or more peaks in its XRPD selected from those at about 14.7, about 16.5, about 17.6, about 23.5 and about 24.3 degrees 2-theta.
Crystalline (R)—N-(4-chlorophenyl)-2-((1S,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide anhydrous hydrochloride salt Form B.
Dependencies are inferred from the claim text.