Viral inhibitors, the synthesis thereof, and intermediates thereto
AssigneeTakeda Pharmaceutical Company Limited
InventorsJeffrey Scott Depue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
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Abstract
The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir. Maribavir is a benzimidazole riboside and is useful as an antiviral.
Claims19
A composition of maribavir and one or more compounds selected from the group consisting of Compound 9, Compound 10, Compound 11, and Compound 12, the composition comprising maribavir and one or more compounds selected from the group consisting of Compound 9, Compound 10, Compound 11, and Compound 12;
- wherein maribavir has the following structure:
- and wherein Compound 9, Compound 10, Compound 11, and Compound 12 have the following structures:
- wherein Compound 9 is present in an amount of 0.1% w/w or less relative to maribavir, Compound 10 is present in an amount of 0.1% w/w or less relative to maribavir, Compound 11 is present in an amount of 0.1% w/w or less relative to maribavir, and Compound 12 is present in an amount of 0.1% w/w or less relative to maribavir.
Dependencies are inferred from the claim text.